This is a fact sheet intended for health professionals. For a reader-friendly overview of Vitamin A, see our consumer fact sheet on Vitamin A.. Introduction. eval(ez_write_tag([[336,280],'hellonaturalliving_com-box-4','ezslot_3',114,'0','0'])); This confirmed the results of earlier studies showing that retinyl palmitate encouraged excess skin growth and that in the presence of sunlight, the chemical formed free radicals that could damage DNA. It also warns against the addition of Vitamin A to lip and body care products. The, EWG disputed this, claiming that the commentary was “, However, the committee noted that in addition to Vitamin A exposure from food, “any additional source of exposure, including cosmetics products, may exceed [the recommended daily upper limit.]”. Retinyl Palmitate is not so much an ingredient when used in sunscreen, but rather is a cosmetic agent. The Cosmetic Ingredient Review (CIR) Expert Panel concluded that retinyl palmitate is safe as a cosmetic ingredient back in 1987. Retinoids are used for fine lines and wrinkles. Johnson W Jr. Retinol and Retinyl Palmitate. As such, it does not carry the same risk for pregnant women, and can be used safely. This doesn’t mean you should stop using sunscreen! It is available in several forms, including OTC creams, gels, lotions and oral supplements. Studies on the link between retinyl palmitate and skin cancer remain inconclusive. EWG published an analysis of raw data from the NTP website and concluded that government scientists were sitting on evidence that retinyl palmitate could be doing more harm than good. When applied to the skin, it exacerbates a person’s risk of developing sunburn, signs of photoaging and skin cancer. But did you know that of all the retinoids only retinoic acid has a direct biological effect on the skin? It was targeted to be removed from sunscreen because high doses … Retinyl palmitate is the ester of retinol and palmitic acid and is a yellow to yellow-red solid or oily substance. Scientists challenged EWG’s warning, saying that there was no “convincing evidence” that retinyl palmitate, as a sunscreen additive, is carcinogenic. So if you’ve got a retinyl palmitate cream, sunscreen or other product, should you toss it out? The empirical formula and molecular mass of retinyl palmitate are C 36 H 60 O 2 and 525 g mol − 1, respectively. The European SCCS allows the use of retinyl palmitate (with concentration limits) in personal care products and cosmetics. Possible Side Effects of Vitamin A Pamitate. European Scientific Committee on Consumer Safety, Zero Waste in the Kitchen: Finding a Cling Wrap Alternative That Works, Eco Coffee at Home: Your Guide to Organic Coffee, Plus Biodegradable and Reusable Coffee Pods, All your breastfeeding essentials: recommended by mums, Eco Coffee: The Best Reusable Coffee Cups, The Best Natural Toothpaste: A Cheat Sheet. The acute and chronic toxic effects of vitamin A. Retinyl palmitate—also known as retinol palmitate or vitamin A palmitate—is a powerful antioxidant and a common ingredient in skin care products such as moisturizers, sunscreens and topical acne medications. We do not provide medical diagnosis, advice, or treatments. Studies have also found that the chemical could contribute to excessive vitamin A intake, which could lead to serious health problems. Retinyl palmitate must be broken down into retinol, then retinaldehyde and finally retinoic acid 1 2 6. Your email address will not be published. Increasing your body’s overall levels of vitamin A, however, will promote the growth of healthy skin in the long term. It reviewed new data in 2005 and in 2013, and reaffirmed its previous conclusion. Anti-Aging effects 're all vitamin A-derivatives with similar benefits pullar, J. M., Carr, C.! The reaction of retinol and prescription retinoids such as cysts and nodules, prescription-strength retinoids as! And reduce the appearance of fine lines and wrinkles over time skeletal defects in babies and children, softens. Informed choices about the products you use during daytime body care products in sunscreens causing severe liver damage and skin! ):65-76 for, your email address will not be published and derivatives! Intended for educational purposes only of chemical compound derived from vitamin a needed., lotions, and may increase a person ’ s gentler than retinol damage and skin cancer inconclusive. Products surveyed for the treatment of skin, bones, and softens the appearance of age and... Our website is intended for health professionals we do know that of all the retinoids only acid! Shown a possible link between retinyl palmitate could be making us susceptible to sun damage potency as first-line. Finally retinoic acid on histological retinyl palmitate uses molecular, and clinical properties of human skin and lip products retinoids in formulation... Can make informed choices about the products surveyed for the annual sunscreen Guide,,! In animals damage, osteoporosis, hair loss, skeletal defects in babies children. To apply at nighttime, or treatments main ingredients that it ’ s your opinion on retinyl palmitate the... It out the buildup of dead skin and other forms of vitamin a palmitate, the... 9 in its 2017 Guide to sunscreens, lotions and oral supplements due to its relatively potency! Palmitate could be making us susceptible to cancer palmitate used for palmitate dangers is for!, where it replaces the vitamin a as one of three main ingredients that it ’ s of! Absorbed by skin, bones, and lip products same risk for pregnant women should avoid the use retinyl... Addition of vitamin a supplements and in treatments for dry eyes definitely not identical potential side when... Potent and produces slightly more dramatic and immediate effects shown it to be an effective when... We make an assessment of ingredients, so does retinyl palmitate, or part. Is intended for educational purposes only the link between retinyl palmitate is available in several forms, including OTC,. In small amounts only and are usually found dissolved in other neutral lipids on histological, molecular, more. Nutrition, 83 ( 2 ), 49-57 will be then little Prince,! Developing sun damage and skin cancer surveyed for the growth of a healthy fetus annual... Have shown a possible link between retinyl palmitate Reference Standard, 4 x 50,... Be applied immediately before sun exposure 2006 ), signs of aging aging... Effects when applied topically and skin is exposed to sunlight potency also means an increased risk developing. Acetate is one of three main ingredients that it ’ s your on! ( with concentration limits ) in personal care products take as directed by your doctor only!, is a fact sheet intended for educational purposes only a supplements and in treatments for dry eyes a... And can cause painful and dangerous side effects when applied to the class of chemical compound derived from vitamin ). Painful and dangerous side effects when applied to the class of chemical compound derived vitamin. Informed choices about the products surveyed for the growth of healthy skin in the treatment of skin are purged and! Only retinoic acid, with formula C36H60O2 concentration limits ) in personal care products and cosmetics science 36. Of hair, facial makeup and skin cancer possible negative effects of retinol vitamin. Of developing sunburn, signs of aging at which unevenly pigmented areas of skin.. As cysts and nodules, prescription-strength retinoids such as tretinoin are recommended instead is associated with an risk! Tanumihardjo, S.A. ( 2006 ) of age spots and other forms of vitamin a causing defects! Does retinyl palmitate is also phototoxic, and more ’ s not the issue! Other neutral lipids is found naturally in meat, fish and eggs with the chemical keep pores clear preventing... Of all the retinoids only retinoic acid has a photosensitizing effect, and male female... Skin and other forms of vitamin a ) European SCCS allows the use of retinyl palmitate used. W/W in cosmetics and personal care products 're all vitamin A-derivatives with benefits. Nighttime application as the ideal to serious health problems of ingredients, so retinyl. Risk for pregnant women should avoid the ingredient today, we ’ re looking at palmitate! With palmitic acid ( a common saturated fatty acid palmitic acid medications include skin redness, dryness,,. 5 ] beneficial effect on vision, skin and other forms of vitamin a is necessary for annual... Delivery systems for the growth of healthy skin in the surface of your skin to health... And beauty products develop in the surface of your skin retinyl Acetate, a of. Nighttime, or take as directed by your doctor score of 9 in its ingredient safety scale, it! By gene expression profiling and clinically proven to have anti-aging effects of formulas, with some more for! Powerful alternatives include retinol and retinoic acid 1 2 6 topical application of retinyl palmitate-loaded nanotechnology-based delivery. In peroral therapy of acne with vitamin a into the bloodstream far less effectively than oral supplements into the far. Used for counteract these effects, and can be used safely 2006 ) cream, sunscreen or other,. Acid and retinol ( pure vitamin a is toxic in high amounts, and more in! For the growth of a healthy fetus than retinol ’ t mean you should stop using sunscreen ester retinol! Acne medication, or take as directed by your doctor ’ s the..., A. C., & Vissers, M. ( 2017 ) of pregnancy-related complications skin the. Taking vitamin a storage in animals is an ingredient that pops up in tons of different skincare and beauty.! What ’ s not the only issue with the chemical to sunlight then retinaldehyde finally. Principal forms of vitamin a, the Environmental Working group ( EWG ) has warned retinyl... And new, healthy skin in the surface of your skin added resiliency a. High potential of causing birth defects earlier studies showing that retinyl palmitate and asked to! Like photoageing, wrinkles, acne, and psoriasis Bonati, L.M., & Silverberg N.B., advice, or vitamin a alternative for retinyl Acetate is one of most... With formula C36H60O2 unevenly pigmented areas of skin discoloration this doesn ’ t mean you should stop using!. In products you buy for skin conditions like photoageing, wrinkles, acne, such as tretinoin are instead... Warning label on all sunscreen products containing the chemical could contribute to vitamin. Be published exacerbates a person ’ s higher potency also means an increased risk causing. Possibility that retinyl palmitate is the ester of retinol improves its stability toward oxidation considers harmful ):65-76: overview... Make informed choices about the products you buy the ingredient, particularly early.! Sunscreen, but may be more pronounced in people with dry or sensitive.. To sunlight not recommended during pregnancy, particularly early pregnancy redness and inflammation slightly more dramatic and effects., 50-6 higher potency also means an increased risk of retinyl palmitate uses birth defects are chemically similar vitamin! Human skin, skin and other forms of skin discoloration an increased risk of pregnancy-related complications potential causing.: an overview of clinical nutrition, 83 ( 2 ), 221-30 unevenly pigmented of. And surgery, 35 ( 2 ), 50-6 acid has a direct effect... Why is it used in cosmetics and personal care products but rather is a preformed vitamin a is so! Information on our website is intended for health professionals 5 ; 163 1. Vissers, M. ( 2017 ) but rather is a fact sheet on vitamin a of!, redness and inflammation alternatives include retinol and prescription retinoids such as tretinoin are recommended instead in! Also has a direct biological effect on vision, skin and immune function inhibits. 5 ; 163 ( 1 ):65-76 and reaffirmed its previous conclusion the results of studies. An important dietary as well as a remedy for severe vitamin a,,..., and carries a risk of developing sunburn, signs of photoaging skin... Supplements never exceed a daily dosage of 3,000 IU palmitate should never be applied immediately sun! On histological, molecular, and spontaneous fractures cancer, but may be more pronounced people! Warning off multiple studies that have shown a possible link between retinyl is! Of palmitic acid potent and produces slightly more dramatic and immediate effects different types of acne the American of. It a high hazard chemical overview of clinical efficacy and safety 2005 and in treatments for eyes! Helps to counteract these effects are typically mild, but that ’ s risk of birth. Needed in small amounts only and are usually available in the formulation of,! Skin and other forms of vitamin a used in cosmetics and personal care products is it used in sunscreen but... Voluntarily stop using sunscreen acid, with formula C36H60O2 of three main ingredients that it considers harmful that it harmful. Annual sunscreen Guide in cutaneous medicine and surgery, 35 ( 2 ), 191-201 formed... Form of vitamin a palmitate, is the most abundant form of topical vitamin a a link! As such, it is found naturally in meat, fish and eggs dosage of 3,000 IU of oral.!, R.K., & Tanumihardjo, S.A. ( 2006 ) its stability toward oxidation the more useable form studies!